Profiling of Rigosertib Identifies Distinct Classes of Responders in Myelodysplastic Syndrome

Myelodysplastic syndromes (MDS) are clonal neoplasms with dysfunctional hematopoietic stem cells characterized by ineffective hematopoiesis, cytopenias, and have a substantial risk of transformation to AML.

Myelodysplastic syndromes (MDS) are clonal neoplasms with dysfunctional hematopoietic stem cells characterized by ineffective hematopoiesis, cytopenias, and have a substantial risk of transformation to AML. The hypomethylating agents (HMAs) azacytidine and decitabine are the standard...